
hereditary disease that destroys red blood cells by causing them to take on a rigid `sickle` shape. The disease is characterized by many of the ... [14 related articles]
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http://www.britannica.com/eb/a-z/s/90

An inherited disease in which the red blood cells have an abnormal crescent shape, block small blood vessels, and do not last as long as normal red blood cells. Sickle cell anemia is caused by a mutation (change) in one of the genes for hemoglobin (the substance inside red blood cells that binds to oxygen and carries it from the lungs to the tissue...
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http://www.cancer.gov/dictionary?expand=S

Contents • Who is at risk? • Signs and symptoms • Diagnosis • Treatment • Living with sickle cell anemia The sickle-shaped red blood cells tend to get stuck in blood vessels, blocking the flow of blood The presence of two sickle cell genes (SS) is needed for ...
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http://www.daviddarling.info/encyclopedia/S/sickle_cell_disease.html

an autosomal dominant, chronic form of hemolytic anemia in which large numbers of sickle cells circulate in the blood; it is most common among persons of African and Mediterranean descent. See also sickle cell disease.
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A genetic
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http://www.encyclo.co.uk/local/22139

An hereditary, chronic form of hemolytic anemia characterized by breakdown of the red blood cells
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http://www.encyclo.co.uk/local/22391

Type: Term Definitions: 1. an autosomal recessive anemia characterized by crescent- or sickle-shaped erythrocytes and accelerated hemolysis, due to substitution of a single amino acid (valine for glutamic acid) in the sixth position of the β-chain of hemoglobin, the gene of which is on chromosome 11; affected homozygotes have 85-95% hemoglobin...
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http://www.medilexicon.com/medicaldictionary.php?t=3683

Sickle cell anemia: A genetic blood disease due to the presence of an abnormal form of hemoglobin, namely hemoglobin S. Hemoglobin is the molecule in red blood cells that transports oxygen from the lungs to the farthest areas of the body. Sickle cell anemia affects millions of people throughout the world. It is particularly common among people whos...
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http://www.medterms.com/script/main/art.asp?articlekey=15689

A hereditary, autosomal recessive trait that occurs primarily in people of African ancestry, in which it evolved apparently as a protection (in the carrier state) against malaria. In the homozygous state, hemoglobin S is made instead of hemoglobin A; this leads to the characteristic sickling of red blood cells, hemolytic anemia, and organ damage.
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[
n] - a congenital form of anemia occurring mostly in blacks
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http://www.webdictionary.co.uk/definition.php?query=sickle-cell%20anemia

sickle-cell anemia, sickle-cell anaemia 1. A chronic inherited anemia that occurs primarily in individuals of African, Mediterranean, or southwest Asian ancestry who are homozygous for the gene controlling hemoglobin S and that is characterized especially by episodic blocking of small blood vessels by sickle cells. 2. A chronic hereditary form of a...
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a disease of certain ethnic groups that causes anemia
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https://sciencetrek.org/sciencetrek/topics/blood/glossary.cfm
sickle-cell anaemia noun a congenital form of anemia occurring mostly in blacks; characterized by abnormal blood cells having a crescent shape
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https://www.encyclo.co.uk/local/20974

Anemia caused by abnormal red blood cells shaped like a sickle or a cylinder. Occurs most often in people of African or Mediterranean descent.
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https://www.encyclo.co.uk/local/22789

Anemia caused by abnormal red blood cells shaped like a sickle or a cylinder. Occurs most often in people of African or Mediterranean descent.
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https://www.encyclo.co.uk/local/23319

an inherited blood disorder characterized by defective hemoglobin, where there are two copies of abnormal hemoglobin genes present.
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https://www.stanfordchildrens.org/en/topic/default?id=glossary---hematology

an inherited autosomal recessive condition that causes abnormal hemoglobin in blood cells, leading to infections and organ damage.
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https://www.stanfordchildrens.org/en/topic/default?id=glossary-medical-gene

A genetic disorder (most commonly seen in populations of African descent) that causes abnormally shaped red blood cells.
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